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Institute of Medical and Biological Engineering

Centre of Excellence in Medical and Biological Engineering

Immunology

Overview

This is an opportunity for you to study for a prestigious and exciting four year integrated PhD and MSc in medical and biological engineering within the Institute of Medical and Biological Engineering.

2014 entry: We are not recruiting on this programme this year but we do have a very similar programme details of which can be found on the link below:

www.regenerative-medicine.leeds.ac.uk

PhD studentships include fees and a maintenance grant at the 2013 EPSRC rate of between £13,000- £14,000 (tax free) per annum for UK students. EU candidates will be eligible for a fees-only award.

Benefits
- Research within an interactive interdisciplinary and innovative research training environment, applying advanced multidisciplinary basic sciences to market-led engineering research challenges in tissue engineering and regenerative medicine;
- Supervised and guided by world-class academics;
- Access to excellent facilities, including state of the art medical and biological engineering laboratories and clean rooms for the development of materials for clinical use;
- Ideal training for a career in research and development in the medical and biological engineering field as well as providing invaluable experience in industry and clinical applications.

Programme

Structure and content of this programme, which is subject to change.

Research Areas

Research within the Centre for Doctoral Training is organised under the following headings

Joint Replacement and Substitution

Tissue Re-engineering

Functional Spinal Interventions

We also have cross group research themes:

Cartilage

Virtual Modelling

Research Projects

Each year the programme offers a choice of interdisciplinary research projects to their year 1 students. Each project has at least 2 interdisciplinary supervisors.

Students are asked to make choices as soon as possible (but no later than the end of December during their first year). Project allocation is subject to supervisor and programme approval.

Below is a current list which is offered to year 1 students this year (2013-2014) provides an idea of the type of projects which are available.

Tissue Replacement

Understanding the failure mechanism of total ankle replacement

Claire Brockett

John Fisher, Joanne Tipper, Anthony Redmond

Advanced simulation for SAFER® “Stratified Approaches For Enhanced Reliability of Joint Replacement

John Fisher

Louise Jennings

Dynamics of Gait and Wear.

Todd Stewart

Anthony Redmond, Martin Stone, John Fisher

Multibody Dynamics of the Hip Capsule

Todd Stewart

Anthony Redmond, Martin Stone, John Fisher

Biocompatibility of Biolox Delta Ceramic on Ceramic Hip Replacements

Joanne Tipper

Sophie Williams, James Anderson, John Fisher

Influence of Kinematics on Wear Particle Size and Biocompatibility of Poly-ether-ether-ketone (PEEK) and Carbon Fibre Reinforced PEEK

Joanne Tipper

Sophie Williams, John Fisher

Replacement of Damaged Cartilage in the Hip

Sophie Williams

Joanne Tipper, Jonathan Jeffers

Cartilage Substitution

Biomechanical Markers for Ankle Degeneration

Claire Brockett

John Fisher, Ruth Wilcox, Anthony Redmond

Parameterised fibril orientation for articular cartilage in computer simulation of the natural hip joint

Alison Jones

John Fisher

Representation of femoral fracture conditions in the testing of fixation plate devices

Alison Jones

Tissue Engineering

SAFER Stratified Approaches For Enhanced Reliability of Biological Scaffolds

John Fisher

Eileen Ingham

Biomechanisms of tissue engineered aortic heart valve

Louise Jennings

John Fisher, Eileen Ingham

Development of dynamic culture conditions for vascular graft production

Stacy Wilshaw

Development of acellular porcine liver grafts

Stacy Wilshaw

Investigation of antimicrobial activity of functionalized chitosan hydrogels

David Wood

Giuseppe Tronci, Deirdre Devine

Bone tissue engineering in vitro and in vivo a novel multilayer cell sheet technology

Xuebin Yang

Peter Giannoudis, Xiaodong Jia

Spine/Orthopaedic Biomechanics

Development of a 3D CNS model to study the effect of matrix environment on CNS cell behaviour and stem cell differentiation

Joanne Tipper

James Phillips, Steve Rimmer, Richard Hall

The intervertebral disc: developing laboratory methods to maintain the mechanical integrity

Ruth Wilcox

Eileen Ingham

Simulation of the fatigue performance of the spinal vertebrae after augmentation

Ruth Wilcox

David Barton

Funding

2014 entry: We are not recruiting on this programme this year but we do have a very similar programme details of which can be found on the link below:

www.regenerative-medicine.leeds.ac.uk

PhD studentships include fees and a maintenance grant at the 2013 EPSRC rate of between £13,000- £14,000 (tax free) per annum for UK students. EU candidates will be eligible for a fees-only award.

Entry requirements

A masters degree and/or at least an upper second class (2.1) honours degree in any of the following subjects: engineering, chemistry, biology, physics, maths or computing.

How to apply

For admissions enquiries and how to apply please contact our Graduate School Office, phd@engineering.leeds.ac.uk

For informal enquiries please contact Dr Joanne Tipper, j.l.tipper@leeds.ac.uk or c.a.harris@leeds.ac.uk